A data-driven method for quantifying the impact of a genetic circuit on its host

A data-driven method for quantifying the impact of a genetic circuit on its host

Genetic circuits aredesigned to implement certain logic in living cells, keeping burden on the host cell minimal. However, manipulating the genome often will have a significant impact for various reasons (usage of the cell machinery to express new genes, toxicity of genes, interactions with native g...

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Bibliographic Details
Main Authors: Dorfan, Yuval, Espah Borujeni, Amin, Park, YongJin, Saxena, Uma, Gondon, Ben, Voigt, Christopher A., Yeung, Enoch
Other Authors: Massachusetts Institute of Technology. Department of Mechanical Engineering
Format: Article
Language:English
Published: IEEE 2020
Online Access:https://hdl.handle.net/1721.1/127200

Internet

https://hdl.handle.net/1721.1/127200

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