Dynamic Enhancer DNA Methylation as Basis for Transcriptional and Cellular Heterogeneity of ESCs

Dynamic Enhancer DNA Methylation as Basis for Transcriptional and Cellular Heterogeneity of ESCs

Song et al. used an allelic reporter approach to show super-enhancers allelic DNA methylation dynamics underlies locus-specific heterogeneity, which functionally impacts transcription and cellular states of mouse embryonic stem cells.

Bibliographic Details
Main Authors: Song, Yuelin, van den Berg, Patrick R., Markoulaki, Styliani, Soldner, Frank, Dall’Agnese, Alessandra, Henninger, Jonathan E., Drotar, Jesse, Rosenau, Nicholas, Cohen, Malkiel A., Young, Richard A., Semrau, Stefan, Stelzer, Yonatan, Jaenisch, Rudolf
Other Authors: Massachusetts Institute of Technology. Department of Biology
Format: Article
Language:English
Published: Elsevier BV 2020
Online Access:https://hdl.handle.net/1721.1/127657

Internet

https://hdl.handle.net/1721.1/127657

Similar Items