Dynamic Enhancer DNA Methylation as Basis for Transcriptional and Cellular Heterogeneity of ESCs
Song et al. used an allelic reporter approach to show super-enhancers allelic DNA methylation dynamics underlies locus-specific heterogeneity, which functionally impacts transcription and cellular states of mouse embryonic stem cells.
| Main Authors: | , , , , , , , , , , , , |
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| Other Authors: | |
| Format: | Article |
| Language: | English |
| Published: |
Elsevier BV
2020
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| Online Access: | https://hdl.handle.net/1721.1/127657 |
| _version_ | 1826212832067190784 |
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| author | Song, Yuelin van den Berg, Patrick R. Markoulaki, Styliani Soldner, Frank Dall’Agnese, Alessandra Henninger, Jonathan E. Drotar, Jesse Rosenau, Nicholas Cohen, Malkiel A. Young, Richard A. Semrau, Stefan Stelzer, Yonatan Jaenisch, Rudolf |
| author2 | Massachusetts Institute of Technology. Department of Biology |
| author_facet | Massachusetts Institute of Technology. Department of Biology Song, Yuelin van den Berg, Patrick R. Markoulaki, Styliani Soldner, Frank Dall’Agnese, Alessandra Henninger, Jonathan E. Drotar, Jesse Rosenau, Nicholas Cohen, Malkiel A. Young, Richard A. Semrau, Stefan Stelzer, Yonatan Jaenisch, Rudolf |
| author_sort | Song, Yuelin |
| collection | MIT |
| description | Song et al. used an allelic reporter approach to show super-enhancers allelic DNA methylation dynamics underlies locus-specific heterogeneity, which functionally impacts transcription and cellular states of mouse embryonic stem cells. |
| first_indexed | 2024-09-23T15:38:55Z |
| format | Article |
| id | mit-1721.1/127657 |
| institution | Massachusetts Institute of Technology |
| language | English |
| last_indexed | 2024-09-23T15:38:55Z |
| publishDate | 2020 |
| publisher | Elsevier BV |
| record_format | dspace |
| spelling | mit-1721.1/1276572022-09-29T15:14:40Z Dynamic Enhancer DNA Methylation as Basis for Transcriptional and Cellular Heterogeneity of ESCs Song, Yuelin van den Berg, Patrick R. Markoulaki, Styliani Soldner, Frank Dall’Agnese, Alessandra Henninger, Jonathan E. Drotar, Jesse Rosenau, Nicholas Cohen, Malkiel A. Young, Richard A. Semrau, Stefan Stelzer, Yonatan Jaenisch, Rudolf Massachusetts Institute of Technology. Department of Biology Song et al. used an allelic reporter approach to show super-enhancers allelic DNA methylation dynamics underlies locus-specific heterogeneity, which functionally impacts transcription and cellular states of mouse embryonic stem cells. NIH (Grants HD045022, 1U19AI131135, 5R01MH104610, and 1R01GM114864) 2020-09-21T14:36:44Z 2020-09-21T14:36:44Z 2019-08 2020-09-18T18:46:40Z Article http://purl.org/eprint/type/JournalArticle 1097-2765 https://hdl.handle.net/1721.1/127657 Song, Yuelin et al. "Dynamic Enhancer DNA Methylation as Basis for Transcriptional and Cellular Heterogeneity of ESCs." Molecular Cell 75, 5 (September 2019): P905-920.e6 © 2019 Elsevier Inc en http://dx.doi.org/10.1016/j.molcel.2019.06.045 Molecular Cell Creative Commons Attribution-NonCommercial-NoDerivs License http://creativecommons.org/licenses/by-nc-nd/4.0/ application/pdf Elsevier BV PMC |
| spellingShingle | Song, Yuelin van den Berg, Patrick R. Markoulaki, Styliani Soldner, Frank Dall’Agnese, Alessandra Henninger, Jonathan E. Drotar, Jesse Rosenau, Nicholas Cohen, Malkiel A. Young, Richard A. Semrau, Stefan Stelzer, Yonatan Jaenisch, Rudolf Dynamic Enhancer DNA Methylation as Basis for Transcriptional and Cellular Heterogeneity of ESCs |
| title | Dynamic Enhancer DNA Methylation as Basis for Transcriptional and Cellular Heterogeneity of ESCs |
| title_full | Dynamic Enhancer DNA Methylation as Basis for Transcriptional and Cellular Heterogeneity of ESCs |
| title_fullStr | Dynamic Enhancer DNA Methylation as Basis for Transcriptional and Cellular Heterogeneity of ESCs |
| title_full_unstemmed | Dynamic Enhancer DNA Methylation as Basis for Transcriptional and Cellular Heterogeneity of ESCs |
| title_short | Dynamic Enhancer DNA Methylation as Basis for Transcriptional and Cellular Heterogeneity of ESCs |
| title_sort | dynamic enhancer dna methylation as basis for transcriptional and cellular heterogeneity of escs |
| url | https://hdl.handle.net/1721.1/127657 |
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