DNA Phosphorothioate Modifications Are Widely Distributed in the Human Microbiome

The DNA phosphorothioate (PT) modification existing in many prokaryotes, including bacterial pathogens and commensals, confers multiple characteristics, including restricting gene transfer, influencing the global transcriptional response, and reducing fitness during exposure to chemical mediators of...

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Bibliographic Details
Main Authors: Sun, Yihua, Kong, Lingxin, Wu, Guojun, Cao, Bo, Pang, Xiaoyan, Deng, Zixin, Dedon, Peter C, Zhang, Chenhong, You, Delin
Other Authors: Massachusetts Institute of Technology. Department of Biological Engineering
Format: Article
Published: Multidisciplinary Digital Publishing Institute 2020
Online Access:https://hdl.handle.net/1721.1/127687