Mechanisms for curing yeast prions

Prions are infectious proteins that self-propagate by changing from their normal folded conformation to a misfolded conformation. The misfolded conformation, which is typically rich in β-sheet, serves as a template to convert the prion protein into its misfolded conformation. In yeast, the...

Full description

Bibliographic Details
Main Authors: Greene, Lois E., Saba, Farrin, Silberman, Rebecca Estelle, Zhao, Xiaohong
Other Authors: Koch Institute for Integrative Cancer Research at MIT
Format: Article
Published: Multidisciplinary Digital Publishing Institute 2020
Online Access:https://hdl.handle.net/1721.1/127693