Secondary Amino Alcohols: Traceless Cleavable Linkers for Use in Affinity Capture and Release

Capture and release of peptides is often a critical operation in the pathway to discovering materials with novel functions. However, the best methods for efficient capture impede facile release. To overcome this challenge, we report linkers based on secondary amino alcohols for the release of peptid...

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Bibliographic Details
Main Authors: Pomplun, Sebastian Johannes, Shugrue, Christopher R., Schmitt, Adeline M., Schissel, Carly K., Farquhar, Charlotte E., Pentelute, Bradley L.
Other Authors: Massachusetts Institute of Technology. Department of Chemistry
Format: Article
Language:English
Published: Wiley 2020
Online Access:https://hdl.handle.net/1721.1/128119