Distinct Tissue-Specific Roles for the Disease-Associated Autophagy Genes ATG16L2 and ATG16L1

Distinct Tissue-Specific Roles for the Disease-Associated Autophagy Genes ATG16L2 and ATG16L1

The clear role of autophagy in human inflammatory diseases such as Crohn disease was first identified by genome-wide association studies and subsequently dissected in multiple mechanistic studies. ATG16L1 has been particularly well studied in knockout and hypomorph settings as well as models recapit...

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Bibliographic Details
Main Authors: Khor, Bernard, Conway, Kara L., Omar, Abdifatah S., Biton, Moshe, Haber, Adam L., Rogel, Noga, Baxt, Leigh A., Begun, Jakob, Kuballa, Petric, Gagnon, John D., Lassen, Kara G., Regev, Aviv, Xavier, Ramnik Joseph
Other Authors: Massachusetts Institute of Technology. Institute for Medical Engineering & Science
Format: Article
Language:English
Published: American Association of Immunologists 2020
Online Access:https://hdl.handle.net/1721.1/128135

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https://hdl.handle.net/1721.1/128135

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