Seven‐Step Continuous Flow Synthesis of Linezolid Without Intermediate Purification

Herein, the blockbuster antibacterial drug linezolid is synthesized from simple starting blocks by a convergent continuous flow sequence involving seven (7) chemical transformations. This is the highest total number of distinct reaction steps ever performed in continuous flow without conducting solv...

Full description

Bibliographic Details
Main Authors: Russell, M. Grace, Jamison, Timothy F
Other Authors: Massachusetts Institute of Technology. Department of Chemistry
Format: Article
Published: Wiley 2020
Online Access:https://hdl.handle.net/1721.1/128199