Daisy-chain gene drives for the alteration of local populations

If they are able to spread in wild populations, CRISPR-based gene-drive elements would provide new ways to address ecological problems by altering the traits of wild organisms, but the potential for uncontrolled spread tremendously complicates ethical development and use. Here, we detail a self-exha...

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Bibliographic Details
Main Authors: Noble, Charleston, Min, John, Olejarz, Jason, Buchthal, Joanna, Chavez, Alejandro, Smidler, Andrea L., DeBenedictis, Erika A., Church, George M., Nowak, Martin A., Esvelt, Kevin Michael
Other Authors: Massachusetts Institute of Technology. Media Laboratory
Format: Article
Language:English
Published: National Academy of Sciences 2020
Online Access:https://hdl.handle.net/1721.1/128226