Terbium(III) Luminescence-Based Assay for Esterase Activity

Esterases catalyze the hydrolysis of esters to form a carboxylic acid and alcohol. These enzymes play a key role in both the detoxification of xenobiotic compounds and the metabolism of drugs and prodrugs. Numerous fluorogenic probes have been developed to monitor esterase activity. Most are based o...

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Bibliographic Details
Main Authors: Hetrick, Kenton, Aguilar Ramos, Miguel A., Raines, Ronald T
Other Authors: Massachusetts Institute of Technology. Department of Chemistry
Format: Article
Language:English
Published: American Chemical Society (ACS) 2020
Online Access:https://hdl.handle.net/1721.1/128548