Angiogenin activates the astrocytic Nrf2/antioxidant-response element pathway and thereby protects murine neurons from oxidative stress
The angiogenin (ANG) gene is mutated frequently in individuals with amyotrophic lateral sclerosis (ALS), a fatal neurode-generative disease characterized by the progressive loss of motor neurons. Delivering human ANG to mice that display ALS-like symptoms extends their lifespan and improves motor fu...
| Main Authors: | , , , |
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| 其他作者: | |
| 格式: | 文件 |
| 语言: | English |
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American Society for Biochemistry & Molecular Biology (ASBMB)
2020
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| 在线阅读: | https://hdl.handle.net/1721.1/128552 |