Cell-specific prediction and application of drug-induced gene expression profiles

Gene expression profiling of in vitro drug perturbations is useful for many biomedical discovery applications including drug repurposing and elucidation of drug mechanisms. However, limited data availability across cell types has hindered our capacity to leverage or explore the cell-specificity of t...

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Bibliographic Details
Main Authors: Hodos, Rachel, Zhang, Ping, Lee, Hao-Chih, Duan, Qiaonan, Wang, Zichen, Clark, Neil R., Ma’ayan, Avi, Wang, Fei, Kidd, Brian, Hu, Jianying, Sontag, David Alexander, Dudley, Joel
Other Authors: Massachusetts Institute of Technology. Institute for Medical Engineering & Science
Format: Article
Language:English
Published: World Scientific 2020
Online Access:https://hdl.handle.net/1721.1/128664