Cell-specific prediction and application of drug-induced gene expression profiles
Gene expression profiling of in vitro drug perturbations is useful for many biomedical discovery applications including drug repurposing and elucidation of drug mechanisms. However, limited data availability across cell types has hindered our capacity to leverage or explore the cell-specificity of t...
Main Authors: | Hodos, Rachel, Zhang, Ping, Lee, Hao-Chih, Duan, Qiaonan, Wang, Zichen, Clark, Neil R., Ma’ayan, Avi, Wang, Fei, Kidd, Brian, Hu, Jianying, Sontag, David Alexander, Dudley, Joel |
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Other Authors: | Massachusetts Institute of Technology. Institute for Medical Engineering & Science |
Format: | Article |
Language: | English |
Published: |
World Scientific
2020
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Online Access: | https://hdl.handle.net/1721.1/128664 |
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