Deuteriodifluoromethylation and gem‐Difluoroalkenylation of Aldehydes Using ClCF2H in Continuous Flow

The deuteriodifluoromethyl group (CF₂D) represents a challenging functional group due to difficult deuterium incorporation and unavailability of precursor reagents. Herein, we report the use of chlorodifluoromethane (ClCF₂H) gas in the continuous flow deuteriodifluoromethylation and gem-difluoroalke...

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Bibliographic Details
Main Authors: Fu, Wai Chung, Jamison, Timothy F
Other Authors: Massachusetts Institute of Technology. Department of Chemistry
Format: Article
Language:English
Published: Wiley 2020
Online Access:https://hdl.handle.net/1721.1/128668