Protection of tissue physicochemical properties using polyfunctional crosslinkers

Understanding complex biological systems requires the system-wide characterization of both molecular and cellular features. Existing methods for spatial mapping of biomolecules in intact tissues suffer from information loss caused by degradation and tissue damage. We report a tissue transformation s...

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Bibliographic Details
Main Authors: Park, Young-Gyun, Sohn, Chang Ho, Chen, Ritchie, McCue, Margaret Grace, Yun, Dae Hee, Drummond, Gabrielle, Ku, Taeyun, Evans, Nicholas B, Oak, Hayeon Caitlyn, Trieu, Wendy, Choi, Heejin, Jin, Xin, Lilascharoen, Varoth, Wang, Ji, Truttmann, Matthias C, Qi, Helena Wen, Ploegh, Hidde L, Golub, Todd R, Chen, Shih-Chi, Frosch, Matthew P, Kulik, Heather Janine, Lim, Byung Kook, Chung, Kwanghun
Other Authors: Massachusetts Institute of Technology. Institute for Medical Engineering & Science
Format: Article
Language:English
Published: Springer Science and Business Media LLC 2020
Online Access:https://hdl.handle.net/1721.1/128842