Human Primordial Germ Cells Are Specified from Lineage-Primed Progenitors

In vitro gametogenesis is the process of making germline cells from human pluripotent stem cells. The foundation of this model is the quality of the first progenitors called primordial germ cells (PGCs), which in vivo are specified during the peri-implantation window of human development. Here, we s...

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Bibliographic Details
Main Authors: Chen, Di, Sun, Na, Hou, Lei, Kim, Rachel, Faith, Jared, Aslanyan, Marianna, Tao, Yu, Zheng, Yi, Fu, Jianping, Liu, Wanlu, Kellis, Manolis, Clark, Amander
Other Authors: Massachusetts Institute of Technology. Computer Science and Artificial Intelligence Laboratory
Format: Article
Language:English
Published: Elsevier BV 2021
Online Access:https://hdl.handle.net/1721.1/129350