The Potential Role of Coagulation Factor Xa in the Pathophysiology of COVID-19: A Role for Anticoagulants as Multimodal Therapeutic Agents

SARS-CoV-2 infection (COVID-19) results in local and systemic activation of inflammation and coagulation. In this review article, we will discuss the potential role of coagulation factor Xa (FXa) in the pathophysiology of COVID-19. FXa, a serine protease, has been shown to play a role in the cleavag...

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Bibliographic Details
Main Authors: Frydman, Galit H., Streiff, Michael B., Connors, Jean M., Piazza, Gregory
Other Authors: Massachusetts Institute of Technology. Center for Biomedical Engineering
Format: Article
Published: Thieme 2021
Online Access:https://hdl.handle.net/1721.1/129571