Spatiotemporal Up-Regulation of Mu Opioid Receptor 1 in Striatum of Mouse Model of Huntington’s Disease Differentially Affecting Caudal and Striosomal Regions

Spatiotemporal Up-Regulation of Mu Opioid Receptor 1 in Striatum of Mouse Model of Huntington’s Disease Differentially Affecting Caudal and Striosomal Regions

The striatum of humans and other mammals is divided into macroscopic compartments made up of a labyrinthine striosome compartment embedded in a much larger surrounding matrix compartment. Anatomical and snRNA-Seq studies of the Huntington’s disease (HD) postmortem striatum suggest a preferential dec...

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Bibliographic Details
Main Authors: Morigaki, Ryoma, Lee, Jannifer, Yoshida, Tomoko, Wuethrich, Christian, Hu, Dan, Crittenden, Jill R, Friedman, Alexander, Kubota, Yasuo, Graybiel, Ann M
Other Authors: McGovern Institute for Brain Research at MIT
Format: Article
Published: Frontiers Media SA 2021
Online Access:https://hdl.handle.net/1721.1/129663

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https://hdl.handle.net/1721.1/129663

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