Generative models for graph-based protein design

Engineered proteins offer the potential to solve many problems in biomedicine, energy, and materials science, but creating designs that succeed is difficult in practice. A significant aspect of this challenge is the complex coupling between protein sequence and 3D structure, with the task of finding...

Full description

Bibliographic Details
Main Authors: Ingraham, John, Garg, Vikas Kamur, Barzilay, Regina, Jaakkola, Tommi S
Other Authors: Massachusetts Institute of Technology. Computer Science and Artificial Intelligence Laboratory
Format: Article
Language:English
Published: Neural Information Processing Systems Foundation, Inc. 2021
Online Access:https://hdl.handle.net/1721.1/129731.2