Solution structure and biochemical characterization of a spare part protein that restores activity to an oxygen-damaged glycyl radical enzyme

Solution structure and biochemical characterization of a spare part protein that restores activity to an oxygen-damaged glycyl radical enzyme

Abstract: Glycyl radical enzymes (GREs) utilize a glycyl radical cofactor to carry out a diverse array of chemically challenging enzymatic reactions in anaerobic bacteria. Although the glycyl radical is a powerful catalyst, it is also oxygen sensitive such that oxygen exposure causes cleavage of the...

Full description

Bibliographic Details
Main Authors: Bowman, Sarah E. J., Backman, Lindsey R., Bjork, Rebekah E., Andorfer, Mary, Yori, Santiago, Caruso, Alessio, Stultz, Collin M, Drennan, Catherine L
Other Authors: Massachusetts Institute of Technology. Department of Chemistry
Format: Article
Language:English
Published: Springer Science and Business Media LLC 2021
Online Access:https://hdl.handle.net/1721.1/129986

Internet

https://hdl.handle.net/1721.1/129986

Similar Items