Nuclear Mechanopathology and Cancer Diagnosis

Abnormalities in nuclear and chromatin organization are hallmarks of many diseases including cancer. This review provides our understanding of how the cellular microenvironment regulates nuclear morphology and with it the spatial organization of chromosomes and genes, resulting in cell-type specific...

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Bibliographic Details
Main Authors: Uhler, Caroline, Shivashankar, G.V.
Other Authors: Massachusetts Institute of Technology. Laboratory for Information and Decision Systems
Format: Article
Published: Elsevier BV 2021
Online Access:https://hdl.handle.net/1721.1/130125