Thalamic regulation of switching between cortical representations enables cognitive flexibility

Interactions between the prefrontal cortex (PFC) and mediodorsal thalamus are critical for cognitive flexibility, yet the underlying computations are unknown. To investigate frontothalamic substrates of cognitive flexibility, we developed a behavioral task in which mice switched between different se...

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Bibliographic Details
Main Authors: Rikhye, Rajeev Vijay, Halassa, Michael
Other Authors: McGovern Institute for Brain Research at MIT
Format: Article
Language:English
Published: Springer Science and Business Media LLC 2021
Online Access:https://hdl.handle.net/1721.1/130385