Mapping the epigenomic and transcriptomic interplay during memory formation and recall in the hippocampal engram ensemble

The epigenome and three-dimensional (3D) genomic architecture are emerging as key factors in the dynamic regulation of different transcriptional programs required for neuronal functions. In this study, we used an activity-dependent tagging system in mice to determine the epigenetic state, 3D genome...

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Bibliographic Details
Main Authors: Marco, Asaf, Meharena, Hiruy S., Dileep, Vishnu, Raju, Ravikiran M., Davila Velderrain, Jose, Zhang, Amy Letao, Adaikkan, Chinnakkaruppan, Young, Jennie Zin-Ney, Gao, Fan, Kellis, Manolis, Tsai, Li-Huei
Other Authors: Picower Institute for Learning and Memory
Format: Article
Language:English
Published: Springer Science and Business Media LLC 2021
Online Access:https://hdl.handle.net/1721.1/130450