Platform for micro-invasive membrane-free biochemical sampling of brain interstitial fluid

Neurochemical dysregulation underlies many pathologies and can be monitored by measuring the composition of brain interstitial fluid (ISF). Existing in vivo tools for sampling ISF do not enable measuring large rare molecules, such as proteins and neuropeptides, and thus cannot generate a complete pi...

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Bibliographic Details
Main Authors: Raman, Ritu, Rousseau, Erin Byrne, Wade, Michael, Tong, Allison, Cotler, Max Joseph, Kuang, Jenevieve, Lugo, Alejandro Aponte, Zhang, Elizabeth Y., Graybiel, Ann M, White, Forest M., Langer, Robert S, Cima, Michael J.
Other Authors: Harvard University--MIT Division of Health Sciences and Technology
Format: Article
Language:English
Published: American Association for the Advancement of Science (AAAS) 2021
Online Access:https://hdl.handle.net/1721.1/130467