Reverse-transcribed SARS-CoV-2 RNA can integrate into the genome of cultured human cells and can be expressed in patient-derived tissues

Prolonged detection of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) RNA and recurrence of PCR-positive tests have been widely reported in patients after recovery from COVID-19, but some of these patients do not appear to shed infectious virus. We investigated the possibility that SAR...

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Detalhes bibliográficos
Main Authors: Zhang, Liguo, Richards, Alexsia, Barrasa, M. Inmaculada, Hughes, Stephen H., Young, Richard A., Jaenisch, Rudolf
Outros Autores: Massachusetts Institute of Technology. Department of Biology
Formato: Artigo
Idioma:English
Publicado em: National Academy of Sciences 2021
Acesso em linha:https://hdl.handle.net/1721.1/130644