Designing Biological Circuits: Synthetic Biology Within the Operon Model and Beyond

In 1961, Jacob and Monod proposed the operon model of gene regulation. At the model's core was the modular assembly of regulators, operators, and structural genes. To illustrate the composability of these elements, Jacob and Monod linked phenotypic diversity to the architectures of regulatory c...

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Bibliographic Details
Main Authors: English, Max A., Gayet, Raphaël V., Collins, James J.
Other Authors: Massachusetts Institute of Technology. Department of Biological Engineering
Format: Article
Language:English
Published: Annual Reviews 2021
Online Access:https://hdl.handle.net/1721.1/131266