Phenotyping Neurodegeneration in Human iPSCs

Induced pluripotent stem cell (iPSC) technology holds promise for modeling neurodegenerative diseases. Traditional approaches for disease modeling using animal and cellular models require knowledge of disease mutations. However, many patients with neurodegenerative diseases do not have a known genet...

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Bibliographic Details
Main Authors: Li, Jonathan, Fraenkel, Ernest
Other Authors: Massachusetts Institute of Technology. Computational and Systems Biology Program
Format: Article
Language:English
Published: Annual Reviews 2021
Online Access:https://hdl.handle.net/1721.1/131273