Mix-and-read, one-minute SARS-CoV-2 diagnostic assay: development of PIFE-based aptasensor

We developed a one-minute, one-step SARS-CoV-2 antigen assay based on protein-induced fluorescence enhancement of a DNA aptamer. The system showed significant selectivity and sensitivity towards both nucleocapsid protein and SARS-CoV-2 virus lysate, but with marked improvements in speed and manufact...

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Bibliographic Details
Main Authors: Lee, J. Michelle, Kim, Chae Rin, Kim, Sion, Min, Junhong, Lee, Min-Ho, Lee, SangWook
Other Authors: Massachusetts Institute of Technology. Department of Chemistry
Format: Article
Published: Royal Society of Chemistry (RSC) 2021
Online Access:https://hdl.handle.net/1721.1/131288