Functional Transcription Factor Target Networks Illuminate Control of Epithelial Remodelling

Cell identity is governed by gene expression, regulated by transcription factor (TF) binding at cis-regulatory modules. Decoding the relationship between TF binding patterns and gene regulation is nontrivial, remaining a fundamental limitation in understanding cell decision-making. We developed the...

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Bibliographic Details
Main Authors: Overton, Ian M., Sims, Andrew H., Owen, Jeremy A., Heale, Bret S. E., Ford, Matthew J., Lubbock, Alexander L. R., Pairo-Castineira, Erola, Essafi, Abdelkader
Other Authors: Massachusetts Institute of Technology. Department of Physics
Format: Article
Published: Multidisciplinary Digital Publishing Institute 2021
Online Access:https://hdl.handle.net/1721.1/131303