Multi-Omics Characterization of Inflammatory Bowel Disease-Induced Hyperplasia/Dysplasia in the Rag2−/−/Il10−/− Mouse Model

Multi-Omics Characterization of Inflammatory Bowel Disease-Induced Hyperplasia/Dysplasia in the Rag2−/−/Il10−/− Mouse Model

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Epigenetic dysregulation is hypothesized to play a role in the observed association between inflammatory bowel disease (IBD) and colon tumor development. In the present work, DNA methylome, hydroxymethylome, and transcriptome analyses were conducted in proximal colon tissues harvested from the <i...

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Bibliografische gegevens
Hoofdauteurs: Han, Qiyuan, Kono, Thomas J. Y., Knutson, Charles G., Parry, Nicola M., Seiler, Christopher L., Fox, James G., Tannenbaum, Steven R., Tretyakova, Natalia Y.
Formaat: Artikel
Gepubliceerd in: Multidisciplinary Digital Publishing Institute 2021
Online toegang:https://hdl.handle.net/1721.1/131312

Internet

https://hdl.handle.net/1721.1/131312

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