Development of Methods Derived from Iodine-Induced Specific Cleavage for Identification and Quantitation of DNA Phosphorothioate Modifications

Development of Methods Derived from Iodine-Induced Specific Cleavage for Identification and Quantitation of DNA Phosphorothioate Modifications

DNA phosphorothioate (PT) modification is a novel modification that occurs on the DNA backbone, which refers to a non-bridging phosphate oxygen replaced by sulfur. This exclusive DNA modification widely distributes in bacteria but has not been found in eukaryotes to date. PT modification renders DNA...

Full description

Bibliographic Details
Main Authors: Zhu, Sucheng, Zheng, Tao, Kong, Lingxin, Li, Jinli, Cao, Bo, DeMott, Michael S., Sun, Yihua, Chen, Ying, Deng, Zixin, Dedon, Peter C., You, Delin
Other Authors: Massachusetts Institute of Technology. Department of Biological Engineering
Format: Article
Published: Multidisciplinary Digital Publishing Institute 2021
Online Access:https://hdl.handle.net/1721.1/131316

Internet

https://hdl.handle.net/1721.1/131316

Similar Items