NAMPT Over-Expression Recapitulates the BRAF Inhibitor Resistant Phenotype Plasticity in Melanoma

NAMPT Over-Expression Recapitulates the BRAF Inhibitor Resistant Phenotype Plasticity in Melanoma

Serine&ndash;threonine protein kinase B-RAF <b>(</b><i>BRAF)</i>-mutated metastatic melanoma (MM) is a highly aggressive type of skin cancer. Treatment of MM patients using BRAF/MEK inhibitors (BRAFi/MEKi) eventually leads to drug resistance, limiting any clinical benefit...

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Bibliographic Details
Main Authors: Audrito, Valentina, Messana, Vincenzo Gianluca, Moiso, Enrico, Vitale, Nicoletta, Arruga, Francesca, Brandimarte, Lorenzo, Gaudino, Federica, Pellegrino, Elisa, Vaisitti, Tiziana, Riganti, Chiara, Piva, Roberto, Deaglio, Silvia
Other Authors: Koch Institute for Integrative Cancer Research at MIT
Format: Article
Published: Multidisciplinary Digital Publishing Institute 2021
Online Access:https://hdl.handle.net/1721.1/131328

Internet

https://hdl.handle.net/1721.1/131328

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