Nicotinamide riboside with pterostilbene (NRPT) increases NAD+ in patients with acute kidney injury (AKI): a randomized, double-blind, placebo-controlled, stepwise safety study of escalating doses of NRPT in patients with AKI

Nicotinamide riboside with pterostilbene (NRPT) increases NAD+ in patients with acute kidney injury (AKI): a randomized, double-blind, placebo-controlled, stepwise safety study of escalating doses of NRPT in patients with AKI

Abstract Background Preclinical studies have identified both NAD+ and sirtuin augmentation as potential strategies for the prevention and treatment of AKI. Nicotinamide riboside (NR) is a NAD+ precursor vitamin and pterostilbene (PT) is potent sirtui...

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Bibliographic Details
Main Authors: Simic, Petra, Vela Parada, Xavier F, Parikh, Samir M, Dellinger, Ryan, Guarente, Leonard P, Rhee, Eugene P
Other Authors: Massachusetts Institute of Technology. Department of Biology
Format: Article
Language:English
Published: BioMed Central 2021
Online Access:https://hdl.handle.net/1721.1/131586

Internet

https://hdl.handle.net/1721.1/131586

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