The application of HPLC/MS analysis with a multi-enzyme digest strategy to characterize different interferon product variants produced from Pichia pastoris

Abstract Interferons are signaling proteins that belong to the large class of cytokines and human interferons which are classified based on the type of receptor interactions: type I, II and III. IFNα2b belongs to the type I interferon class with a major therapeutic application for the...

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Bibliographic Details
Main Authors: Wang, Yu, Liu, Di, Crowell, Laura E, Love, Kerry R, Wu, Shiaw-lin, Hancock, William S
Other Authors: Koch Institute for Integrative Cancer Research at MIT
Format: Article
Language:English
Published: Springer Vienna 2021
Online Access:https://hdl.handle.net/1721.1/131809