CloneSifter: enrichment of rare clones from heterogeneous cell populations

Abstract Background Many biological processes, such as cancer metastasis, organismal development, and acquisition of resistance to cytotoxic therapy, rely on the emergence of rare sub-clones from a larger population. Understanding how the genetic and epigenetic features of diverse clones affect...

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Bibliographic Details
Main Authors: Feldman, David, Tsai, FuNien, Garrity, Anthony J, O’Rourke, Ryan, Brenan, Lisa, Ho, Patricia, Gonzalez, Elizabeth, Konermann, Silvana, Johannessen, Cory M, Beroukhim, Rameen, Bandopadhayay, Pratiti, Blainey, Paul C
Other Authors: Massachusetts Institute of Technology. Department of Physics
Format: Article
Language:English
Published: BioMed Central 2021
Online Access:https://hdl.handle.net/1721.1/131939