The epithelial-mesenchymal transition and the cytoskeleton in bioengineered systems

Abstract The epithelial-mesenchymal transition (EMT) is intrinsically linked to alterations of the intracellular cytoskeleton and the extracellular matrix. After EMT, cells acquire an elongated morphology with front/back polarity, which can be attributed to actin-driven protrusion for...

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Bibliographic Details
Main Authors: Leggett, Susan E., Hruska, Alex M., Guo, Ming, Wong, Ian Y.
Other Authors: Massachusetts Institute of Technology. Department of Mechanical Engineering
Format: Article
Language:English
Published: BioMed Central 2021
Online Access:https://hdl.handle.net/1721.1/132046