In Vivo CRISPR Screen Identifies TgWIP as a Toxoplasma Modulator of Dendritic Cell Migration

In Vivo CRISPR Screen Identifies TgWIP as a Toxoplasma Modulator of Dendritic Cell Migration

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© 2019 Elsevier Inc. Sangaré et al. use a CRISPR screen to determine the in vivo fitness of Toxoplasma genes. They identify a secreted protein, TgWIP, which determines dendritic cell motility and transmigration in the infected host. In mice, TgWIP determines T. gondii dissemination from the site of...

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Bibliographic Details
Main Authors: Sangaré, Lamba Omar, Ólafsson, Einar B., Wang, Yifan, Yang, Ninghan, Julien, Lindsay, Camejo, Ana, Pesavento, Patricia, Sidik, Saima M., Lourido, Sebastian, Barragan, Antonio, Saeij, Jeroen P.J.
Other Authors: Massachusetts Institute of Technology. Department of Biology
Format: Article
Language:English
Published: Elsevier BV 2022
Online Access:https://hdl.handle.net/1721.1/132590.2

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https://hdl.handle.net/1721.1/132590.2

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