A stapled POL κ peptide targets REV1 to inhibit mutagenic translesion synthesis

A stapled POL κ peptide targets REV1 to inhibit mutagenic translesion synthesis

© 2020 Wiley Periodicals LLC Stapled α-helical RIR (Rev1-interacting region) peptides of DNA POL κ bind more effectively to the RIR-interface of the C-terminal recruitment domain of the translesion synthesis DNA polymerase Rev1 than unstapled peptide. The tightest-binding stapled peptide translocate...

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Bibliographic Details
Main Authors: Chatterjee, Nimrat, D'Souza, Sanjay, Shabab, Mohammad, Harris, Cynthia A, Hilinski, Gerard J, Verdine, Gregory L, Walker, Graham C
Other Authors: Massachusetts Institute of Technology. Department of Biology
Format: Article
Language:English
Published: Wiley 2021
Online Access:https://hdl.handle.net/1721.1/132710

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https://hdl.handle.net/1721.1/132710

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