A stapled POL κ peptide targets REV1 to inhibit mutagenic translesion synthesis
© 2020 Wiley Periodicals LLC Stapled α-helical RIR (Rev1-interacting region) peptides of DNA POL κ bind more effectively to the RIR-interface of the C-terminal recruitment domain of the translesion synthesis DNA polymerase Rev1 than unstapled peptide. The tightest-binding stapled peptide translocate...
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Bibliographic Details
| Main Authors: |
Chatterjee, Nimrat,
D'Souza, Sanjay,
Shabab, Mohammad,
Harris, Cynthia A,
Hilinski, Gerard J,
Verdine, Gregory L,
Walker, Graham C |
| Other Authors: |
Massachusetts Institute of Technology. Department of Biology |
| Format: | Article
|
| Language: | English |
| Published: |
Wiley
2021
|
| Online Access: | https://hdl.handle.net/1721.1/132710
|