Accumulation of collagen molecular unfolding is the mechanism of cyclic fatigue damage and failure in collagenous tissues

Accumulation of collagen molecular unfolding is the mechanism of cyclic fatigue damage and failure in collagenous tissues

© 2020 The Authors. Overuse injuries to dense collagenous tissues are common, but their etiology is poorly understood. The predominant hypothesis that micro-damage accumulation exceeds the rate of biological repair is missing a mechanistic explanation. Here, we used collagen hybridizing peptides to...

Full description

Bibliographic Details
Main Authors: Zitnay, Jared L, Jung, Gang Seob, Lin, Allen H, Qin, Zhao, Li, Yang, Yu, S Michael, Buehler, Markus J, Weiss, Jeffrey A
Other Authors: Massachusetts Institute of Technology. Laboratory for Atomistic and Molecular Mechanics
Format: Article
Language:English
Published: American Association for the Advancement of Science (AAAS) 2021
Online Access:https://hdl.handle.net/1721.1/132713

Internet

https://hdl.handle.net/1721.1/132713

Similar Items