Oncogenic HSP90 facilitates metabolic alterations in aggressive B-cell lymphomas

Oncogenic HSP90 facilitates metabolic alterations in aggressive B-cell lymphomas

HSP90 is critical for the maintenance of cellular proteostasis. In cancer cells, HSP90 also becomes a nucleating site for the stabilization of multiprotein complexes including signaling pathways and transcription complexes. Here we describe the role of this HSP90 form, referred to as oncogenic HSP90...

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Detalhes bibliográficos
Principais autores: Calvo-Vidal, M Nieves, Zamponi, Nahuel, Krumsiek, Jan, Stockslager, Max A, Revuelta, Maria V, Phillip, Jude M, Marullo, Rossella, Tikhonova, Ekaterina, Kotlov, Nikita, Patel, Jayeshkumar, Yang, Shao Ning, Yang, Lucy, Taldone, Tony, Thieblemont, Catherine, Leonard, John P, Martin, Peter, Inghirami, Giorgio, Chiosis, Gabriela, Manalis, Scott R, Cerchietti, Leandro
Outros Autores: Massachusetts Institute of Technology. Department of Mechanical Engineering
Formato: Artigo
Idioma:English
Publicado em: American Association for Cancer Research (AACR) 2021
Acesso em linha:https://hdl.handle.net/1721.1/132977

Internet

https://hdl.handle.net/1721.1/132977

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