Oncogenic HSP90 facilitates metabolic alterations in aggressive B-cell lymphomas

Oncogenic HSP90 facilitates metabolic alterations in aggressive B-cell lymphomas

HSP90 is critical for the maintenance of cellular proteostasis. In cancer cells, HSP90 also becomes a nucleating site for the stabilization of multiprotein complexes including signaling pathways and transcription complexes. Here we describe the role of this HSP90 form, referred to as oncogenic HSP90...

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Bibliographic Details
Main Authors: Calvo-Vidal, M Nieves, Zamponi, Nahuel, Krumsiek, Jan, Stockslager, Max A, Revuelta, Maria V, Phillip, Jude M, Marullo, Rossella, Tikhonova, Ekaterina, Kotlov, Nikita, Patel, Jayeshkumar, Yang, Shao Ning, Yang, Lucy, Taldone, Tony, Thieblemont, Catherine, Leonard, John P, Martin, Peter, Inghirami, Giorgio, Chiosis, Gabriela, Manalis, Scott R, Cerchietti, Leandro
Other Authors: Massachusetts Institute of Technology. Department of Mechanical Engineering
Format: Article
Language:English
Published: American Association for Cancer Research (AACR) 2021
Online Access:https://hdl.handle.net/1721.1/132977

Internet

https://hdl.handle.net/1721.1/132977

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