Structural and biophysical insights into the mode of covalent binding of rationally designed potent BMX inhibitors

<p>We identified potent, functionalisable BMX inhibitors and revealed their covalent mode of binding to BMX by X-ray crystallography.</p>

Bibliographic Details
Main Authors:	Seixas, João D, Sousa, Bárbara B, Marques, Marta C, Guerreiro, Ana, Traquete, Rui, Rodrigues, Tiago, Albuquerque, Inês S, Sousa, Marcos FQ, Lemos, Ana R, Sousa, Pedro MF, Bandeiras, Tiago M, Wu, Di, Doyle, Shelby K, Robinson, Carol V, Koehler, Angela N, Corzana, Francisco, Matias, Pedro M, Bernardes, Gonçalo JL
Other Authors:	Koch Institute for Integrative Cancer Research at MIT
Format:	Article
Language:	English
Published:	Royal Society of Chemistry (RSC) 2022
Online Access:	https://hdl.handle.net/1721.1/133096.2

Internet

https://hdl.handle.net/1721.1/133096.2