Structural and biophysical insights into the mode of covalent binding of rationally designed potent BMX inhibitors

<p>We identified potent, functionalisable BMX inhibitors and revealed their covalent mode of binding to BMX by X-ray crystallography.</p>

Opis bibliograficzny
Główni autorzy:	Seixas, João D, Sousa, Bárbara B, Marques, Marta C, Guerreiro, Ana, Traquete, Rui, Rodrigues, Tiago, Albuquerque, Inês S, Sousa, Marcos FQ, Lemos, Ana R, Sousa, Pedro MF, Bandeiras, Tiago M, Wu, Di, Doyle, Shelby K, Robinson, Carol V, Koehler, Angela N, Corzana, Francisco, Matias, Pedro M, Bernardes, Gonçalo JL
Kolejni autorzy:	Koch Institute for Integrative Cancer Research at MIT
Format:	Artykuł
Język:	English
Wydane:	Royal Society of Chemistry (RSC) 2022
Dostęp online:	https://hdl.handle.net/1721.1/133096.2

Structural and biophysical insights into the mode of covalent binding of rationally designed potent BMX inhibitors od Seixas, João D, Sousa, Bárbara B, Marques, Marta C, Guerreiro, Ana, Traquete, Rui, Rodrigues, Tiago, Albuquerque, Inês S, Sousa, Marcos FQ, Lemos, Ana R, Sousa, Pedro MF, Bandeiras, Tiago M, Wu, Di, Doyle, Shelby K, Robinson, Carol V, Koehler, Angela N, Corzana, Francisco, Matias, Pedro M, Bernardes, Gonçalo JL

Wydane 2021

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