Conformational Motions and Water Networks at the α/β Interface in E. coli Ribonucleotide Reductase

© 2020 American Chemical Society. Ribonucleotide reductases (RNRs) catalyze the conversion of all four ribonucleotides to deoxyribonucleotides and are essential for DNA synthesis in all organisms. The active form of E. coli Ia RNR is composed of two homodimers that form the active α2β2 complex. Cata...

Full description

Bibliographic Details
Main Authors: Reinhardt, Clorice R, Li, Pengfei, Kang, Gyunghoon, Stubbe, JoAnne, Drennan, Catherine L, Hammes-Schiffer, Sharon
Other Authors: Howard Hughes Medical Institute
Format: Article
Language:English
Published: American Chemical Society (ACS) 2021
Online Access:https://hdl.handle.net/1721.1/133250