Chemical modifications of adenine base editor mRNA and guide RNA expand its application scope

Chemical modifications of adenine base editor mRNA and guide RNA expand its application scope

Show other versions (1)

© 2020, The Author(s). CRISPR-Cas9-associated base editing is a promising tool to correct pathogenic single nucleotide mutations in research or therapeutic settings. Efficient base editing requires cellular exposure to levels of base editors that can be difficult to attain in hard-to-transfect cells...

Full description

Bibliographic Details
Main Authors: Jiang, Tingting, Henderson, Jordana M, Coote, Kevin, Cheng, Yi, Valley, Hillary C, Zhang, Xiao-Ou, Wang, Qin, Rhym, Luke H, Cao, Yueying, Newby, Gregory A, Bihler, Hermann, Mense, Martin, Weng, Zhiping, Anderson, Daniel G, McCaffrey, Anton P, Liu, David R, Xue, Wen
Format: Article
Language:English
Published: Springer Science and Business Media LLC 2021
Online Access:https://hdl.handle.net/1721.1/133358

Internet

https://hdl.handle.net/1721.1/133358

Similar Items