Structural basis for non-radical catalysis by TsrM, a radical SAM methylase

Structural basis for non-radical catalysis by TsrM, a radical SAM methylase

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© 2021, The Author(s), under exclusive licence to Springer Nature America, Inc. Tryptophan 2C methyltransferase (TsrM) methylates C2 of the indole ring of l-tryptophan during biosynthesis of the quinaldic acid moiety of thiostrepton. TsrM is annotated as a cobalamin-dependent radical S-adenosylmethi...

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Bibliographic Details
Main Authors: Knox, Hayley L, Chen, Percival Yang-Ting, Blaszczyk, Anthony J, Mukherjee, Arnab, Grove, Tyler L, Schwalm, Erica L, Wang, Bo, Drennan, Catherine L, Booker, Squire J.
Other Authors: Massachusetts Institute of Technology. Department of Chemistry
Format: Article
Language:English
Published: Springer Science and Business Media LLC 2022
Online Access:https://hdl.handle.net/1721.1/133379.2

Internet

https://hdl.handle.net/1721.1/133379.2

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