Synergistic lipid compositions for albumin receptor mediated delivery of mRNA to the liver

© 2020, The Author(s). Lipid-like nanoparticles (LNPs) have potential as non-viral delivery systems for mRNA therapies. However, repeated administrations of LNPs may lead to accumulation of delivery materials and associated toxicity. To address this challenge, we have developed biodegradable lipids...

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Bibliographic Details
Main Authors: Miao, Lei, Lin, Jiaqi, Huang, Yuxuan, Li, Linxian, Delcassian, Derfogail, Ge, Yifan, Shi, Yunhua, Anderson, Daniel G
Other Authors: Koch Institute for Integrative Cancer Research at MIT
Format: Article
Language:English
Published: Springer Science and Business Media LLC 2021
Online Access:https://hdl.handle.net/1721.1/133439