IgG-Engineered Protective Antigen for Cytosolic Delivery of Proteins into Cancer Cells

© 2020 American Chemical Society. All rights reserved. Therapeutic immunotoxins composed of antibodies and bacterial toxins provide potent activity against malignant cells, but joining them with a defined covalent bond while maintaining the desired function is challenging. Here, we develop novel imm...

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Bibliographic Details
Main Authors: Lu, Zeyu, Truex, Nicholas L, Melo, Mariane B, Cheng, Yiran, Li, Na, Irvine, Darrell J, Pentelute, Bradley L
Other Authors: Massachusetts Institute of Technology. Department of Chemistry
Format: Article
Language:English
Published: American Chemical Society (ACS) 2022
Online Access:https://hdl.handle.net/1721.1/133532.2