Monitoring and modeling of lymphocytic leukemia cell bioenergetics reveals decreased ATP synthesis during cell division

© 2020, The Author(s). The energetic demands of a cell are believed to increase during mitosis, but the rates of ATP synthesis and consumption during mitosis have not been quantified. Here, we monitor mitochondrial membrane potential of single lymphocytic leukemia cells and demonstrate that mitochon...

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Bibliographic Details
Main Authors: Kang, Joon Ho, Katsikis, Georgios, Li, Zhaoqi, Sapp, Kiera M, Stockslager, Max A, Lim, Daniel, Vander Heiden, Matthew G, Yaffe, Michael B, Manalis, Scott R, Miettinen, Teemu P
Other Authors: Koch Institute for Integrative Cancer Research at MIT
Format: Article
Language:English
Published: Springer Science and Business Media LLC 2021
Online Access:https://hdl.handle.net/1721.1/133549