Transcriptional activation of macropinocytosis by the Hippo pathway following nutrient limitation

Cancer cells must adapt metabolism to thrive despite nutrient limitations in the tumor microenvironment. In this issue of Genes & Development, King and colleagues (pp. 1345-1358) report a role for transcriptional regulators of the Hippo pathway to facilitate protein scavenging and support prolif...

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Bibliographic Details
Main Authors: Sivanand, Sharanya, Vander Heiden, Matthew G
Format: Article
Language:English
Published: Cold Spring Harbor Laboratory 2021
Online Access:https://hdl.handle.net/1721.1/133550